Rare opportunity! This exceptional Prairie Style home, designed by local architect Edward Sporl in the early 1920s, is located in a prime Uptown location on the sought-after Newcomb Boulevard, just steps from St. Charles Avenue, the streetcar line, Tulane and Loyola Universities and Audubon Park. Sporl crafted this brick Wrightian house shortly after the opening of Newcomb Boulevard. Situated on a spacious 21,470 sq ft lot (190 x 113), this home has been meticulously maintained by the same family for nearly 90 years. A significant renovation was done in 1965 by Louisiana MCM architects George Riehl and Donald Graves. The main floor (5,400+ sq ft) features elegant MCM details including large windows, walnut woodwork, custom wall paneling/built-ins, and marble floors. It includes a stunning marble foyer, formal living and dining rooms, kitchen with eat-in area, large den overlooking the beautiful backyard, primary suite with marble fireplace, large sitting area, marble bathroom, and 2 large walk-in closets. Additionally, there are 3 more bedrooms, 3 full baths, ample storage, elevator, and wood floors throughout. The 3600+ sq ft basement (first floor) includes 2 bedrooms, 2 full baths, living room, full kitchen, office, several storage rooms, mechanicals, and an additional laundry room. Outside, there's extra storage, a whole-house generator, a renovated Cabana with 2 baths, a sitting room, and a kitchen. A large, sparkling pool with lounging areas and a generous grassy lawn, plus parking for up to 6 cars and a porte cochere with direct basement access, complete the property. The roof was replaced 2 years ago. 6 Newcomb Boulevard presents a rare and exciting opportunity for its next owner to reimagine and customize this exceptional residence. With its expansive layout and impressive architectural details, this home offers endless renovation potential. The large lot allows for ample outdoor entertaining and landscaping, optimal for creating your dream estate.